The inflammatory response, which is a defensemechanism, is the body's response to tissue damage caused by infection andharmful stimuli.

The inflammatory response is an evolved defensemechanism in organisms to localize and eliminate harmful agents and damagedtissue components. The response occurs as a result of changes in blood flow,increased permeability of blood vessels, and extravasation of fluid, protein,and leukocytes from the circulation to the inflamed area.

Acute inflammation lasting a few days, which has a beneficial role against infection and injury, followed by a rapid healing phase, and while the repair of damaged tissues occurs, inadequate resolution of inflammation and uncontrolled inflammatory reactions, persistent pathogen infection, autoimmune diseases, cardiovascular diseases, diabetes, obesity, neurodegenerative diseases. A long-term response called chronic inflammation occurs, which is the culprit underlying many pathological conditions, including cancer, which is often defined as a wound that does not heal